J. Am. Chem. Soc. 2011, 133, 18114. http://dx.doi.org/10.1021/ja208652n S. Friis, R. Taaning, A. T. Lindhardt and T. Skrydstrup   Silacarboxylic acids have been demonstrated to be easy to handle, air-stable carbon monoxide precursors. Different silacarboxylic acids were synthesized from the corresponding chlorosilanes and carbon dioxide, and their decarbonylation, upon treatment with an array of activators,.. read more →

Org. Lett. 2011, 13, 4454 http://DOI: 10.1021/ol201808y D. U. Nielsen, R. Taaning, A. T. Lindhardt, T. M. Gøgsig and T. Skrydstrup   A simple protocol is reported for the preparation of primary aryl amides under Pd-catalyzed carbonylation chemistry applying a two-chamber system with crystalline and nontransition metal based sources of carbon monoxide and ammonia. The.. read more →

J. Am. Chem. Soc., 2011, 133, 6061–6071 http://DOI: 10.1021/ja200818w Philippe Hermange, Anders T. Lindhardt*, Rolf H. Taaning, Klaus Bjerglund, Daniel Lupp, and Troels Skrydstrup*   A new technique for the ex situ generation of carbon monoxide (CO) and its efficient incorporation in palladium catalyzed carbonylation reactions was achieved using a simple sealed two-chamber system. The.. read more →

Angew. Chem. Int Ed. 2011, 50, 5090. http://DOI: 10.1002/anie.201100327 S. Kramer, Y. Odabachian, J. Overgaard, M. Rottländer, F. Gagosz and T. Skrydstrup   Ynamide derivatives are easily accessible and relatively stable compounds which have proved to be useful buildings blocks for the synthesis of a large variety of nitrogen-containing molecules.1 Owing to the polarization of.. read more →

Org. Lett., 2011, 13, 2444 Philippe Hermange, Thomas M. Gøgsig, Anders T. Lindhardt, Rolf H. Taaning, and Troels Skrydstrup DOI: 10.1021/ol200686h   A carbonylative Heck reaction of aryl iodides and styrene derivatives employing a two-chamber system using a stable, crystalline, and nontransition metal based carbon monoxide source is reported. By applying near-stoichiometric amounts of the.. read more →

J. Am. Chem. Soc., 2011, 133, 6061 DOI: 10.1021/ja200818w Philippe Hermange, Anders T. Lindhardt*, Rolf H. Taaning, Klaus Bjerglund, Daniel Lupp, and Troels Skrydstrup     A new technique for the ex situ generation of carbon monoxide (CO) and its efficient incorporation in palladium catalyzed carbonylation reactions was achieved using a simple sealed two-chamber system… read more →

Colloids and Surface B 2011, 85, 373 doi:10.1016/j.colsurfb.2011.03.014 Lina Sveidal Søbjerg, Anders T. Lindhardt, Troels Skrydstrup, Kai Finster, Rikke Louise Meyer     The development of nanoparticles has greatly improved the catalytic properties of metals due to the higher surface to volume ratio of smaller particles. The production of nanoparticles is most commonly based on.. read more →

Org. Lett., 2011, 13, 1750 http://DOI: 10.1021/ol200269h S. Kramer, S. D. Friis, Z. Xin, Y. Odabachian and T. Skrydstrup A metal-free acetate shift of 3-acetoxy ynamides to access α-iodo, bromo, and chloro acrylamides/acrylimides under very mild conditions is demonstrated. The inherent alkyne activation of ynamides is sufficient to ensure the α-halo acrylamides/acrylimides in high yields.. read more →

J. Phys. Chem. B, 2011, 115, 1767 http://DOI: 10.1021/jp110866g     Recently, ether lipids have been introduced as long–term stable alternatives to the more natural, albeit easier degradable, ester lipids in the preparation of oriented lipid bilayers and bicelles for oriented-sample solid–state NMR spectroscopy. Here we report that ether lipids such as the frequently used.. read more →

Org. Lett., 2011, 13, 732 http://DOI: 10.1021/ol102968g D. Hernandez, R. Mose and T. Skrydstrup   Reductive lithiation of methyl-substituted diarylmethylsilanes using lithium naphthalenide represents a practical method for the preparation of the corresponding silyl lithium reagents. Their addition to chiral sulfinimines affords versatile precursors to silanols and silanediols. The replacement of the currently used diphenylsilane.. read more →