Org. Lett., 2013, 15,  1378 DOI: 10.1021/ol4003465 S. Friis, T. L. Andersen and T. Skrydstrup Aryl iodides and bromides were easily converted to their corresponding aromatic carboxylic acids via a Pd-catalyzed carbonylation reaction using silacarboxylic acids as an in situ source of carbon monoxide. The reaction conditions were compatible with a wide range of functional.. read more →

Signe Korsager, Dennis U. Nielsen, Dr. Rolf H. Taaning, Dr. Anders T. Lindhardt*and Prof. Dr. Troels Skrydstrup*
Chem. Eur. J, 2013, 19, 17687-17691
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Chem. Eur. J., 2013, 19, 17926 Dennis U. Nielsen, Dr. Camille Lescot, Dr. Thomas M. Gøgsig, Dr. Anders T. Lindhardt, Dr. Troels Skrydstrup DOI: 10.1002/chem.201303384 Reaction conditions for the three-component synthesis of aryl 1,3-diketones are reported applying the palladium-catalyzed carbonylative α-arylation of ketones with aryl bromides. The optimal conditions were found by using a catalytic system.. read more →

Dr. Geanna K. Min, Klaus Bjerglund, Dr. Søren Kramer, Dr. Thomas M. Gøgsig*, Dr. Anders T. Lindhardt,* and Prof. Dr. Troels Skrydstrup,*
Chem. Eur. J. , 2013, 19, 17603-17607
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Nanoscale 2013, 5, 8192. DOI: 10.1039/c3nr32922d L. Hansen, E. K. U. Larsen, E. H. Nielsen, F. Iversen, Z. Liu, K. Thomsen, M. Pedersen, T. Skrydstrup, N. C. Nielsen, M. Ploug and J. Kjems   Ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles are currently being used as a magnetic resonance imaging (MRI) contrast agent in vivo, mainly.. read more →

J. Org. Chem., 2013, 78, 10310 DOI: 10.1021/jo401696c A. Ahlburg, A. T. Lindhardt, R. H. Taaning, A. Modvig and T. Skrydstrup Carbonylative Suzuki–Miyaura coupling conditions have been developed that proceed without the exclusion of oxygen and in the presence of nondegassed and nondried solvents. By adapting the method to a two-chamber setup, the direct handling.. read more →

Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 2013, 69, 1060. DOI: 10.1107/S1744309113018551 M. K. Groftehauge, M. O. Therkelsen, R. Taaning, T. Skrydstrup, J. P. Morth and P. Nissen High-quality crystals of Thermus thermophilus EF-Tu in the GTP-bound conformation at 1.7-2.7 Å resolution were used to test 18 small organic molecules, all brominated for confident identification.. read more →

Signe Korsager, Dennis U. Nielsen, Rolf H. Taaning,* and Troels Skrydstrup*
DOI: 10.1002/anie.201304072
Angew. Chem. Int. Ed., 2013, 52, 9763 –9766 read more →

Célia Brancour, Takahide Fukuyama*, Yu Mukai, Troels Skrydstrup, and Ilhyong Ryu*
Org. Lett., 2013, 15, 2794-2797
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J. Org. Chem., 2013, 78 (12),  6112 Signe Korsager, Rolf H. Taaning*, Anders T. Lindhardt, and Troels Skrydstrup* DOI: 10.1021/jo400741t   A protocol has been developed for conducting the palladium-catalyzed reductive carbonylation of aryl iodides and bromides using 9-methylfluorene-9-carbonyl chloride (COgen) as a source of externally delivered carbon monoxide in a sealed two-chamber system (COware),.. read more →

PNAS, 2013, 110, 2798. DOI: 10.1073/pnas.1209955110 S. Zhang, M. Andreasen, J. T. Nielsen, L. Liu, E. H. Nielsen, J. Song, G. Ji, F. Sun, T. Skrydstrup, F. Besenbacher, N. C. Nielsen, D. E. Otzen and M. Dong       Uncontrolled misfolding of proteins leading to the formation of amyloid deposits is associated with more.. read more →

Signe Korsager , Rolf H. Taaning *, and Troels Skrydstrup *
J. Am. Chem. Soc., 2013, 135, 2891-2894
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Org. Lett., 2013, 15, pp 948–951 http://DOI: 10.1021/ol400138m     Mia N. Burhardt, Rolf H. Taaning, and Troels Skrydstrup*   A general protocol for the Pd-catalyzed thiocarbonylation of aryl iodides with stoichiometric carbon monoxide has been established employing a catalytic system composed of Pd(OAc)2 and DPEphos with low catalyst loading (1 mol %). Both electron-rich.. read more →

Geanna K. Min , Dácil Hernández , and Troels Skrydstrup *
Acc. Chem. Res., 2013, 46 457–470
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